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CD63 抗体 (Biotin)

This anti-CD63 antibody is a 小鼠 单克隆 antibody detecting CD63 in FACS. Suitable for 人.
产品编号 ABIN951367
发货至: 中国

Quick Overview for CD63 抗体 (Biotin) (ABIN951367)

抗原

See all CD63 抗体
CD63

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD63 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-259
  • 特异性

    This antibody MEM-259 reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate Buffered Saline (PBS), pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    CD63

    别名

    CD63

    背景

    CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.Synonyms: Granulophysin, ME491, MLA1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, TSPAN30, Tetraspanin-30

    基因ID

    967
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